Medicinal Chemistry I (1 hr lecture)

  • College of Pharmacy |


This course covers the different approved methods of naming drug molecules. The process of drug discovery and development is highlighted. It comprises an introduction to the physiochemical properties of drugs relative to their biological effects. The students are exposed to the concepts of structure-activity relationships and drug-receptor interactions. Highlights and a quick review of modern screening and modelling operations are also explained together with the concept of bio-isosterism and its application in designing new drugs. The course also covers drugs used in hepatic disorders including viral hepatitis, pancreatitis, gastrointestinal bleeding, peptic ulcer, gastro-esophageal reflux disease, inflammatory bowel diseases and irritable bowel syndrome as well as gastrointestinal symptoms including nausea, vomiting, constipation, and diarrhea.


PharmD Clinical


  • Knowledge and Understanding By the end of the course, the students should be able to: a1- Describe discovery, classification and nomenclature of drugs. a2- Explain the effect of physicochemical properties on drugs absorption, distribution, metabolism and elimination of the drug. a3- Explain drug-receptor interactions and methods for optimization of these interactions. Intellectual Skills By the end of the course, the students should be able to: b1- Discuss different optimization strategies of physicochemical properties including the use of physicochemical descriptors. b2- Discuss structure activity relationship of GIT, hepatitis and pancreatitis drugs. b3- Understand the concept of isomers, isosterism and bioisosterism. Professional and Practical skills By the end of the course, the students should be able to: c1- Practice different research tools and self-learning. c2- Integrate drug design software and its applications. General and Transferable skills By the end of the course, the students should be able to: d1- Manage time properly. d2- Develop decision making skills to deal with different problems.


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