Description

This course covers the structure and function of the skin, target area of treatment after topical application to skin, basic principles of diffusion through membranes and factors affecting percutaneous absorption, enhancement of skin penetration, transdermal drug delivery systems (TDDS). It also describes the principles and techniques involved in the formulation and manufacturing of traditional dermatological semisolid dosage forms (creams, ointments, gels pastes) and cosmetic products. In addition, the preparation and stabilization of other semi solid preparations such as suppositories and pessaries.

Program

PharmD Clinical

Objectives

• Knowledge and Understanding By the end of the course the student should be able to: a1. Define semisolid dosage forms including creams, ointments, suppositories and pessaries in order to understand their application in different dosage forms. a2. Illustrate the various techniques used in their preparation. a3. Identify the basic factors that control their stability. a4. Enumerate the various vehicles, bases and emulsifiers used in their fabrication and stabilization including creams, ointments, suppositories and pessaries and their relevance in the manufacture of various dosage forms. Intellectual Skills By the end of the course, the students should be able to: b1. Deduce the methods and techniques that could be applied to prepare semisolid dosage forms including creams, ointments, suppositories, and pessaries. b2. Differentiate between the different types of semisolids and the suitability of each type to various dosage forms. b3. Apply laws related to their stabilization and complexation. Professional and Practical skills By the end of the course, the students should be able to: c1. Handling different semisolid dosage forms prescriptions. c2. Gaining the mathematical skills for necessary pharmaceutical calculations of semisolid preparations. c3. Employ quality control testing to evaluate and characterize semisolid dosage forms General and Transferable skills By the end of the course, the students should be able to: d1. Gain problem solving skills during formulation. d2. Extend information gained to design pharmaceutical semisolid dosage forms. d3. Work in team to present the required tasks with effective time management d4. Develop effective communication skills.