Description

The course cover drugs used to treat different endocrinologic disorders (Diabetes, thyroid disorder, Cushing syndrome and different renal disorders and related fluid and electrolyte disturbances (acute and chronic renal failure, uremic syndrome, kidney stones,.), the drugs are discussed relevant to their possible structure – activity relationships, contraindications, prodrug and bioactivation concepts, if any, their possible metabolism and elimination

Program

PharmD

Objectives

• Domain (1): Fundamental knowledge By the end of the course the student should be able to: 1.1 Recognize the chemical structure, pharmacophore moieties and consequently the structure activity relationship for drugs used to modulate different hormonal systems. 1.2 Explain different physicochemical properties, metabolism and drugs’ actions. 1.3 Evaluate the effect of different pharmacokinetic properties on the drug effectiveness and safety in different clinical settings. Domain (2): Professional and Ethical Practice At the end of the course the student should be able to: 2.1 Design structural changes for optimized physicochemical properties and biological activity of certain drugs to treat some diseases. 2.2 Decide the effect of structure modification on the physicochemical properties and biological activity of the drug. Domain (3): Pharmaceutical Care At the end of the course the student should be able to: 3.1 Apply standard laboratory skills and techniques required for quality control analysis of different market drugs. 3.2 Predict the activity of compounds using pharmacophore molecular modeling techniques. Domain (4): Personal Practice At the end of the course the student should be able to: 4.1 Demonstrate responsibility for team performance and peer evaluation of other team members, and express time management skills. 4.2 Retrieve and critically analyze information, identify and solve problems, and work autonomously and effectively in a team. 4.3 Use new technologies and media to demonstrate effective presentation skills. 4.4 Practice self learning needed for continuous professional development.