Advanced Analytical Techniques (2 hrs Lecture+1 hr Practical)

  • College of Pharmacy |

Description

This course addresses the concepts of modern and automated analytical techniques. The student will be provided with the scientific knowledge and trained on the design and use of analytical methods involving UV spectrometry, fluorimeter, voltammetry, and polarography in addition to separation-based techniques such as high-performance liquid chromatography, thin layer chromatography, and capillary electrophoresis. Simulation software is used to develop the student skills in adjusting the methodological conditions to fit the required purpose

Program

Bachelor of Pharmacy - PharmD (Clinical Pharmacy)

Objectives

  • 1.1

    Demonstarte the theories of instrumental methods of different spectroscopic analysis (molecular absorption Spectrophotometry, molecular emission, atomic emission Fluorimetry)            

     

    1.2

    Recognize basis of chromatomatography; concept, instrumentation and applications.

     

    1.3

    Discuss the separation techniques [columnar method e.g.: HPLC, GC, Planar technique e.g.: TLC].          

    2.1

    Analyze different pharmaceutical products concerning the topics of the course in a systematic way.

     

    2.2

    Detect the quality of analyzed sample

     

    2.3

    Recognize the principles of various tools and instruments and select the proper techniques for analysis of different materials.

     

    2.4

    Handle and dispose hazardous materials used in the pharmaceutical field according to safety measures.

    4.1

    Demonstrate responsibility for team performance and express time management skills.

     

    4.2

    Retrieve and critically analyze information, identify and solve problems, and work autonomously and effectively in a team.

     

    4.3

    Use new technologies and media to demonstrate effective presentation skills.

     

    4.4

    Practice independent learning needed for continuous professional development.

Textbook

Principles of General Chemistry. Martin B. Silberberg. Third edition. McGraw Hill. ISBN 978–0–07–340269–7

Course Content

content serial Description
1Analytical process. Review of the methods of instrumental analysis (Lecture)
1Analytical process. Review of the methods of instrumental analysis (Practical)
2Molecular Absorption Spectroscopy. UV, visible (1) (Lecture)
2Absorption curve of potassium permanganate (Practical)
3Molecular Absorption Spectroscopy. UV, visible (2) (Lecture)
3Determination of concentration of potassium permanganate sample using calibration graph (Practical)
4Molecular Absorption Spectroscopy. UV, visible (3) (Lecture)
4Colorimetric determination of cephalexin in dosage forms (Practical)
5Molecular Absorption Spectroscopy. UV, visible (4) (Lecture)
5Spectrophotometric determination of caffeine (Practical)
6Fluorimetric analysis. Chemiluminescent analysis. Refractometry, polarimetry, nephelometry, turbidimetry theoretical principles (1) (Lecture)
6Beer’s Lambert law problems (Practical)
7Fluorimetric analysis. Chemiluminescent analysis. Refractometry, polarimetry, nephelometry, turbidimetry theoretical principles (2) (Lecture)
7Fluorometric determination of Quinine Sulphate (Practical)
8Fluorimetric analysis. Chemiluminescent analysis. Refractometry, polarimetry, nephelometry, turbidimetry theoretical principles (3) (Lecture)
8Atomic absorption spectroscopic analysis (Practical)
9Chromatography (Lecture)
9Atomic absorption spectroscopic analysis principles. Flame photometry (Practical)
10Thin layer chromatography (Lecture)
10Chromatographic methods of analysis. The main characteristics of the chromatographic process (Practical)
11Thin layer chromatography (2) (Lecture)
11High-performance liquid chromatography. Principle and Equipment (Practical)
12High performance liquid chromatography (Lecture)
12High-performance liquid chromatography. Detectors used in liquid chromatography. Chromatographic phase system (1) (Practical)
13HPLC system suitability parameters (Lecture)
13High-performance liquid chromatography. Detectors used in liquid chromatography. Chromatographic phase system (2) (Practical)
14Scientific paper on chromatography (Lecture)
14Gas chromatography and its principles, use of equipment (Practical)
15Identification and quantification methods of gas chromatography (Lecture)
15Thin layer chromatography, Planar chromatography (Practical)

Markets and Career

  • Generation, transmission, distribution and utilization of electrical power for public and private sectors to secure both continuous and emergency demands.
  • Electrical power feeding for civil and military marine and aviation utilities.
  • Electrical works in construction engineering.

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