- Degree Bachelor
- Code: CCS342
- Credit hrs: 2
- Prequisites: CCS241
This course deals with the characteristics and use of drugs intended for hepatic disorders including viral hepatitis, pancreatitis, gastrointestinal bleeding, peptic ulcer, gastro-esophageal reflux disease, inflammatory bowel diseases and irritable bowel syndrome as well as gastrointestinal symptoms including nausea, vomiting, constipation, and diarrhea. The mechanism of action of different agents commonly used for these disorders is provided. Interactive approaches are used to familiarize the students with background information underlying the expected side effects and the interactions between these agents and other drugs, foods, or disease conditions.
Bachelor of Pharmacy - PharmD (Clinical Pharmacy)
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1.1 |
Recognize the major drug groups used in the treatment of gastrointestinal and hepatic disorders. |
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1.2 |
Explain the general and molecular mechanisms of action of drugs used in these disorders. |
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1.3 |
Outline the general pharmacokinetic properties of these drugs and describe their uncommon adverse effects and idiosyncratic reactions. |
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2.1 |
Apply safe and ethical procedures during in vitro pharmacological experiments. |
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2.2 |
Handle biological tissues and pharmacological agents safely according to approved laboratory procedures. |
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2.3 |
Follow appropriate procedures for the safe use and disposal of biological and pharmaceutical materials during practical activities. |
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3.1 |
Relate the mechanisms of action and pharmacological properties of drugs to their therapeutic roles in gastrointestinal and hepatic disorders. |
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3.2 |
Identify potential drug-drug and drug-food interactions in patient profiles. |
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3.3 |
Apply pharmacological knowledge to resolve drug interactions and to prevent or manage potential adverse effects. |
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4.1 |
Use appropriate drug-information databases and drug-interaction software. |
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4.2 |
Provide relevant pharmacological information in a timely manner to support the resolution of drug-related problems. |
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4.3 |
Apply critical-thinking skills to recognize potential drug-related problems. |
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4.4 |
Practice independent and self-directed learning for continuous professional development. |
Rang, H. P., Dale, M. M., Ritter, J. M., Flower, R. J., & Henderson, G. (2016). Rang and Dale's Pharmacology (8th ed.). Elsevier Churchill Livingstone. Brunton, L. L. (Ed.). (2011). Goodman & Gilman's The Pharmacological Basis of Therapeutics (12th ed.). McGraw-Hill; course lecture and tutorial notes.
| content serial | Description |
|---|---|
| 1 | Drugs used in treatment of peptic ulcer part 1 (Lecture) |
| 1 | Introduction to GIT Disorders (Practical) |
| 2 | Drugs used in treatment of peptic ulcer part 2 (Lecture) |
| 2 | Effect of indirectly acting stimulant drugs on isolated rabbit intestine (acetylcholine) (Practical) |
| 3 | Drugs affecting GIT motility 1 (Lecture) |
| 3 | Reversible competitive of atropine and acetylcholine drugs on isolated rabbit intestine (acetylcholine/atropine) (Practical) |
| 4 | Drugs affecting GIT motility 2 (Lecture) |
| 4 | Effect of directly acting stimulant drugs on isolated rabbit intestine (Barium chloride) (Practical) |
| 5 | Pharmacology of anti-emetics (Lecture) |
| 5 | Effect of Nicotine on rabbit intestines (Practical) |
| 6 | Drugs used in management of irritable bowel syndrome (Lecture) |
| 6 | Elimination method (Practical) |
| 7 | Drugs used in management of inflammatory bowel disease 1 (Lecture) |
| 7 | Quiz of unknown (Practical) |
| 8 | Drugs used in management of inflammatory bowel disease 2 (Lecture) |
| 8 | Types of antagonists (Practical) |
| 9 | Drugs used in management of hepatic encephalopathy (Lecture) |
| 9 | Obsim Antagonist Acetylcholine atropine University of Strathclyde (Practical) |
| 10 | Drugs used in management of Ascites (Lecture) |
| 10 | Effect of drugs on GIT motility and the effect of GIT motility on the absorption of drugs (Practical) |
| 11 | Drugs used in management of portal hypertension (Lecture) |
| 11 | Obsim Effect of Opioids on GIT (Practical) |
| 12 | Drugs used in management of viral hepatitis 1 (Lecture) |
| 12 | Practical Quiz of unknown (Practical) |
| 13 | Drugs used in management of viral hepatitis 2 (Lecture) |
| 13 | Different experimental models and routes of drug administration and sample collection (Practical) |
| 14 | Management of acute pancreatitis (Lecture) |
| 14 | Kortext open book activity on uncovered topics (Practical) |
| 15 | Management of chronic pancreatitis (Lecture) |
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