- Degree Bachelor
- Code: CCS241
- Credit hrs: 3
- Prequisites: CCS233
This course provides the students with the knowledge of the basic principles of pharmacology, pharmacodynamics (general and molecular aspects) and pharmacokinetics. Concepts of agonism, antagonism, and modulation of receptor activity are reviewed together with a general overview of the different potential interventions with the function of various neurotransmitters and humoral mediators as examples of mechanisms of drug action. Practical exercises aim to help students apply this acquired knowledge using selected in-vitro animal models as well as simulation techniques.
Bachelor of Pharmacy - PharmD (Clinical Pharmacy)
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1.1 |
Explain the processes and basic parameters of drug absorption, distribution, metabolism, and excretion. |
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1.2 |
Interpret dose-response curves and distinguish agonism, antagonism, potency, and efficacy. |
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1.3 |
Explain the principal neurotransmitters and pharmacological control of the autonomic nervous system. |
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2.1 |
Calculate basic pharmacokinetic parameters from provided data. |
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2.2 |
Apply pharmacokinetic principles in simulation models and simple dosage-regimen problems. |
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2.3 |
Perform pharmacology laboratory activities safely and ethically, following approved procedures for handling and disposal of biological and pharmaceutical materials. |
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3.1 |
Relate pharmacokinetic and pharmacodynamic principles to the safe and rational use of medicines. |
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3.2 |
Explain how mechanisms of action, contraindications, adverse drug reactions, and drug interactions influence medicine use. |
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3.3 |
Identify common adverse drug reactions and propose appropriate monitoring measures in basic cases. |
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4.1 |
Analyze basic pharmacological cases using critical-thinking and problem-solving skills. |
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4.2 |
Communicate pharmacological information clearly in written and oral formats. |
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4.3 |
Work effectively and responsibly as a member of a team during practical activities. |
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4.4 |
Demonstrate self-directed learning by locating and using appropriate scientific resources for continuous professional development. |
Rang, H. P., Dale, M. M., Ritter, J. M., Flower, R. J., & Henderson, G. (2016). Rang and Dale's Pharmacology (8th ed.). Elsevier Churchill Livingstone. Brunton, L. L. (Ed.). (2011). Goodman & Gilman's The Pharmacological Basis of Therapeutics (12th ed.). McGraw-Hill; course lecture and tutorial notes.
| content serial | Description |
|---|---|
| 1 | Introduction to pharmacology (Lecture) |
| 1 | Introduction to the pharmacology lab and types of experiments (Practical) |
| 2 | Pharmacodynamics: general aspects (Lecture) |
| 2 | Autonomic NS Introduction and concept of NT and OBSIM (Practical) |
| 3 | Pharmacodynamics: molecular aspects (1) (Lecture) |
| 3 | Different types of receptors (Practical) |
| 4 | Pharmacodynamics: molecular aspects (2) (Lecture) |
| 4 | Dose response curve on different drugs and measuring parameters (Practical) |
| 5 | Pharmacokinetics: introduction (Lecture) |
| 5 | Pharmacokinetics (Practical) |
| 6 | Pharmacokinetics: absorption and distribution (Lecture) |
| 6 | Autonomic nervous system disorders dysautonomia (Practical) |
| 7 | Pharmacokinetics: metabolism and excretion (Lecture) |
| 7 | Quiz (Practical) |
| 8 | Autonomic nervous system pharmacology (1) (Lecture) |
| 8 | Effect of indirectly acting stimulant drugs on isolated rabbit intestine (acetylcholine) (Practical) |
| 9 | Autonomic nervous system pharmacology (2) (Lecture) |
| 9 | Effect of indirectly acting stimulant drugs on isolated rabbit intestine (acetylcholine) (Practical) |
| 10 | Parasympathetic pharmacology (1) (Lecture) |
| 10 | Reversible competitive of atropine and acetylcholine drugs on isolated rabbit intestine (acetylcholine/atropine) (Practical) |
| 11 | Parasympathetic pharmacology (2) (Lecture) |
| 11 | Effect of directly acting stimulant drugs on isolated rabbit intestine (Barium chloride) (Practical) |
| 12 | Parasympathetic pharmacology (3) (Lecture) |
| 12 | Differentiate between the effect of directly and indirectly acting drugs on isolated rabbit intestine (Practical) |
| 13 | Sympathetic pharmacology (1) (Lecture) |
| 13 | Practical Quiz of unknown (Practical) |
| 14 | Sympathetic pharmacology (2) (Lecture) |
| 14 | Kortext open book activity on uncovered topics (Practical) |
| 15 | Sympathetic pharmacology (3) (Lecture) |
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