Description
This course is intended to provide the student with the necessary knowledge and skills required for the design and monitoring of drug dosage regimens. An overview of general and particular dosing considerations of examples of drugs requiring therapeutic drug monitoring is discussed. A series of activities are used to train the students in the initiation, follow up and adjustment of these drug regimens, together with the necessary modifications in special patient populations (geriatrics, pediatrics, obese, pregnancy…etc.) and in disease conditions affecting drug disposition.
Program
Bachelor of Pharmacy-B Pharm
Objectives
- Intended Learning Outcomes
By the end of the course students will be able to:
a. Knowledge and Understanding
a.1. Define therapeutic drug monitoring (TDM) and identify its application in hospital setting
a.2. Recognize the general pharmacokinetics in special populations
a.3. Describe the general pharmacokinetic properties of some selected drugs
a.4. Determine the effect of renal and hepatic impairment on drug pharmacokinetics
b. Intellectual Skills
b.1. Calculate the elimination half-life, elimination rate constant, absorption rate constant, apparent volume of distribution, and total body clearance from the population pharmacokinetics data
b.2. Monitor the proper pharmacokinetic and pharmacodynamic parameters for a specific patient
b.3. Modify the therapeutic regimen based on the efficiency of the renal and liver elimination of the drug
c. Professional and Practical Skills
c.1. Identify factors that affect the absorption, distribution, metabolism, excretion, and binding of drugs
c.2. Apply pharmacokinetic concepts in order to determine an individualized dosage regimen for a specific patient
d. General and Transferable Skills
d.1. Apply problem solving skills and critical thinking to reach proper pharmaceutical decisions
