Description
This course aims to introduce the student to the basic concepts governing the progress of reactions and parameters used to describe reaction rates within the context relevant to pharmaceutical preparation performance and stability. Students will become familiar with the orders of reaction kinetics and will be provided with the necessary skills to understand and interpret values such as half-life and reaction rate constants. Principles of radioisotope decay will be also discussed.
Program
Bachelor of Pharmacy-B Pharm
Objectives
- a. Knowledge and Understanding
a.1. Define reaction kinetics, order of reaction, shelf-life, half-life.
a.2. Illustrate the various effects such as pH, temperature, ionic strength, catalysis and others on drug and biopharmaceuticals degradation and stability where applicable.
a.3. Identify the basic mechanisms (physical, chemical, microbiological and nuclear) involved in drug degradation.
a.4. Enumerate the various types of potential incompatibilities and their effect on dosage form dissolution and stability.
b. Intellectual Skills
b.1. Deduce the degradation mechanism and or reactions rate using suitable methods.
b.2. Differentiate between the different types of incompatibilities and their effect on dosage form stability.
b.3. Select excipients, techniques and packaging that contribute to drug stabilization.
b.4. Apply laws related to radioisotope decay with implications on the use of radiopharmaceuticals.
c. Professional and Practical Skills
c.1. Calculate different parameters related to chemical reactions and radioactive decay including reaction rate, half-life and others.
c.2. Derive the shelf life of pharmaceutical products from given data.
d. General and Transferable Skills
d.1. Communicate effectively with peers and supervisors.
d.2. Work under stress to achieve effective time management.
