Chemistry of Natural Products I (2 hrs Lecture+2 hrs Practical)

Description

This course introduces the students to the chemistry of biologically active molecules of natural origin. The chemical structure of the basic nuclei of medically relevant alkaloids, glycosides and other classes of chemical compounds of natural origin either from plants, bacteria or marine life are reviewed both from theoretical and practical aspects. A special emphasis will be on the modern isolation and separation techniques. The biosynthetic pathways of different secondary metabolite groups will be discussed. The pharmacological effects, structure activity relationships and chemical testing of relevant examples will be covered.

Program

Bachelor of Pharmacy-B Pharm

Objectives

• a. Knowledge and Understanding a.1. Identify the general methods of isolation, identification and analysis of different natural products. a.2. Understand therapeutic uses and mechanism of action of different natural products. b. Intellectual Skills b.1. Classify the different natural products according to their chemical structures and their biosynthetic pathways. b.3. Correlate natural products to their medicinal uses based on their structural aspects. c. Professional and Practical Skills c.1. Apply the most economic methods of isolation of natural products and their preparatory steps for commercial use c.2. Perform qualitative and quantitative examination of natural products. c.3. Analyze naturally occurring metabolites by different methods of analysis. d. General and Transferable Skills d.1. Communicate with others to transfer knowledge and information provided by the course d.2. Follow ethical, legal and safety guidelines in all practice settings. d.3. Develop problem solving skills including decision making and critical thinking.